{"id":110644,"date":"2015-02-16T11:02:34","date_gmt":"2015-02-16T10:02:34","guid":{"rendered":"https:\/\/medios.uchceu.es\/actualidad-ceu\/?p=110644"},"modified":"2023-04-27T12:16:37","modified_gmt":"2023-04-27T10:16:37","slug":"scientists-at-the-universities-of-ceu-cardenal-herrera-glasgow-and-edinburgh-discovered-that-bacteria-jump-between-species-more-easily-than-previously-thought","status":"publish","type":"post","link":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/scientists-at-the-universities-of-ceu-cardenal-herrera-glasgow-and-edinburgh-discovered-that-bacteria-jump-between-species-more-easily-than-previously-thought\/","title":{"rendered":"Scientists at the Universities of CEU Cardenal Herrera, Glasgow and Edinburgh discovered that bacteria jump between species more easily than previously thought"},"content":{"rendered":"

The discovery transforms our understanding of the minimal genetic changes that are required for bacteria to infect different species.<\/strong><\/p>\n

\"\"
Jos\u00e9 Penad\u00e9s y David Viana junto a los investigadores de la CEU-UCH, las Universidades de Glasgow y Edimburgo y el IVIA, participantes en la investigaci\u00f3n.<\/figcaption><\/figure>\n

A new study suggests that bacteria may be able to jump between host species far easier than was previously thought. Researchers discovered that a single genetic mutation in a strain of bacteria infectious to humans enables it jump species to also become infectious to rabbits. The discovery has major implications for how we assess the risk of bacterial diseases that can pass between humans and animals. It is well known that relatively few mutations are required to support the transmission of viruses \u2013 such as influenza \u2013 from one species to another. Until now it was thought that the process was likely to be far more complicated for bacteria.<\/p>\n

<\/p>\n

Scientists at the universities of CEU Cardenal Herrera (Spain) and Glasgow<\/a> and Edinburgh<\/a> (UK) studied a strain of bacteria called Staphylococcus aureus<\/em> ST121, which is responsible for widespread epidemics of disease in the global rabbit farming industry. The team looked at the genetic make-up of ST121 to work out where the strain originated and the changes that occurred that enabled it to infect rabbits. They found that ST121 most likely evolved through a host jump from humans to rabbits around 40 years ago with a genetic mutation at a single site in the bacterial DNA code the cause for this.<\/p>\n

The discovery transforms our understanding of the minimal genetic changes that are required for bacteria to infect different species. ST121 is found in the respiratory tract and on the skin of some people. While it is usually harmless, the bacteria can cause a variety of conditions from minor skin infections to meningitis and sepsis. In rabbits, the bacteria can cause serious skin infections.<\/p>\n

Professors David Viana<\/a>, of CEU-UCH Veterinary Faculty<\/strong>, and Jose Penades<\/strong>, of the Institute of Infection, Immunity and Inflammation at the University of Glasgow, who co-led the study, said: \u201cThe ability for pathogens to switch host-species and lead to an epidemic in a new host population is of major concern to veterinary and public health professionals. Our results represent a paradigm shift in understanding of the minimal adaptions required for a bacterium to overcome species barriers and establish in new host populations.\u201d<\/p>\n

Professor Ross Fitzgerald, from the University of Edinburgh\u2019s Roslin Institute, who co-led the study, said: \u201cDomestication of animals, industrialisation of agriculture and globalisation have provided new opportunities for the transmission of bacteria between humans and animals. This latest research has important public and veterinary health implications which will require a re-examination of the future threat posed by bacterial host switching events.\u201d<\/p>\n

The study was funded by the University of Glasgow, the Biotechnology and Biological Sciences Research Council and the Medical Research Council.<\/p>\n

\"\"
David Viana, investigador y profesor de la Facultad de Veterinaria de la CEU-UCH.<\/figcaption><\/figure>\n

Reference:<\/strong><\/p>\n

David Viana, Mari\u0301a Comos, Paul R McAdam, Melissa J. Ward, Laura Selva, Caitriona M. Guinane, Beatriz M. Gonza\u0301lez-Mun\u0303oz, Anne Tristan, Simon J. Foster, J. Ross Fitzgerald & Jose\u0301 R. Penade\u0301s (2015) \u201cA single natural nucleotide mutation alters bacterial pathogen host tropism<\/a>\u201d. Nature Genetics. <\/em>DOI: 10.1038\/ng.3219.<\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

The discovery transforms our understanding of the minimal genetic changes that are required for bacteria to infect different species. A new study suggests that bacteria may be able to jump between host species far easier than was previously thought. 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Soriano","author_link":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/author\/tsoriano\/"},"uagb_comment_info":0,"uagb_excerpt":"The discovery transforms our understanding of the minimal genetic changes that are required for bacteria to infect different species. A new study suggests that bacteria may be able to jump between host species far easier than was previously thought. Researchers discovered that a single genetic mutation in a strain of bacteria infectious to humans enables…","_links":{"self":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts\/110644","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/comments?post=110644"}],"version-history":[{"count":4,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts\/110644\/revisions"}],"predecessor-version":[{"id":153862,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts\/110644\/revisions\/153862"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/media\/99502"}],"wp:attachment":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/media?parent=110644"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/categories?post=110644"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/tags?post=110644"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}