{"id":110422,"date":"2014-01-28T10:59:41","date_gmt":"2014-01-28T09:59:41","guid":{"rendered":"https:\/\/medios.uchceu.es\/actualidad-ceu\/?p=110422"},"modified":"2023-05-02T13:47:35","modified_gmt":"2023-05-02T11:47:35","slug":"a-professor-of-medicine-in-the-ceu-uch-found-an-effective-drug-to-fight-against-cocaine-effects-in-rats","status":"publish","type":"post","link":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/a-professor-of-medicine-in-the-ceu-uch-found-an-effective-drug-to-fight-against-cocaine-effects-in-rats\/","title":{"rendered":"A professor of Medicine in the CEU-UCH found an effective drug to fight against cocaine effects in rats"},"content":{"rendered":"<p><b>The topiramate is able to prevent from the neural alterations observed in rats\u2019 brain after 20 days of cocaine administration.<\/b><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-98838\" src=\"https:\/\/medios.uchceu.es\/actualidad-ceu\/wp-content\/uploads\/sites\/2\/2014\/01\/Rosa-Lopez-Pedrajas_Medicina-CEU-UCH-Castello\u0081n.jpg\" alt=\"\" width=\"1756\" height=\"1217\" \/><\/p>\n<p>The <strong>topiramate<\/strong> is an antiepileptic drug which has the opposite <strong>effects of cocaine on the nervous system<\/strong>. A study realized by the <strong>professor of <a href=\"https:\/\/www.uchceu.com\/en\/studies\" target=\"_blank\" rel=\"noopener noreferrer\">Medicine of the CEU Cardenal Herrera University<\/a> in Castell\u00f3n, <a href=\"https:\/\/www.uchceu.es\/directorio\/rosa-lopez\" target=\"_blank\" rel=\"noopener noreferrer\">Rosa L\u00f3pez Pedrajas<\/a>,<\/strong> has shown that the <strong>topiramate<\/strong> is able to prevent, on a molecular scale, the harmful<strong> effects of the cocaine on rats\u2019 brain<\/strong>. Therefore, in the future and once every necessary study concerning human application will be completed, this could be used as cocaine addiction treatment.<\/p>\n<p>Other findings of this research led by the CEU-UCH University professor, show that the cocaine administration in rats damages the spatial memory of experiment for what have been learned before the cocaine use, a fact that has never been described before. It is a new <strong>neural effect of the cocaine<\/strong> which adds to other effects that were already described in previous researches over learning mechanisms and memory, and against which the topiramate has been proved to be efficient, in the case of rats.<\/p>\n<p>In this rats study, the <strong>topiramate<\/strong> has been able to prevent from every alteration appearing after 20 days of cocaine administration, although, the professor L\u00f3pez Pedrajas warns: \u201cThe study must be continued, since it concerns a research on rats, there is still a long way to go before its application to humans\u201d<\/p>\n<p><b>Addiction linked to the learning process and memory<\/b><\/p>\n<p>The CEU-UCH University professor recalls that it has been widely studied that brain regions where the memory formation and storage take place (hippocampus and frontal cortex) are also involved in the addiction process development. Therefore it is necessary to find a treatment that helps in preventing <strong>cocaine effects<\/strong> on these regions of the central nervous system in order to avoid the addiction development and relapses during drug withdrawal periods.<\/p>\n<p>Some of those research results have been published in the <i>Journal of Neurochemistry<\/i><i> <\/i>and make part of the doctoral thesis of <strong>Rosa Mar\u00eda L\u00f3pez Pedrajas, professor of Medicine in the UCH-UCE University<\/strong>.<\/p>\n<p>The research has been led by the doctors Javier Romero G\u00f3mez, from the Catholic University of San Vicente M\u00e1rtir in Valencia, and Mar\u00eda Muriach Saur\u00ed, from the Jaime I University of Castell\u00f3n.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The topiramate is able to prevent from the neural alterations observed in rats\u2019 brain after 20 days of cocaine administration. The topiramate is an antiepileptic drug which has the opposite effects of cocaine on the nervous system. A study realized by the professor of Medicine of the CEU Cardenal Herrera University in Castell\u00f3n, Rosa L\u00f3pez [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":98838,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[1499,1423],"tags":[],"class_list":["post-110422","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health-sciences-scientific-news","category-scientific-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A professor of Medicine in the CEU-UCH found an effective drug to fight against cocaine effects in rats<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/a-professor-of-medicine-in-the-ceu-uch-found-an-effective-drug-to-fight-against-cocaine-effects-in-rats\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A professor of Medicine in the CEU-UCH found an effective drug to fight against cocaine effects in rats\" \/>\n<meta property=\"og:description\" content=\"The topiramate is able to prevent from the neural alterations observed in rats\u2019 brain after 20 days of cocaine administration. The topiramate is an antiepileptic drug which has the opposite effects of cocaine on the nervous system. A study realized by the professor of Medicine of the CEU Cardenal Herrera University in Castell\u00f3n, Rosa L\u00f3pez [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/a-professor-of-medicine-in-the-ceu-uch-found-an-effective-drug-to-fight-against-cocaine-effects-in-rats\/\" \/>\n<meta property=\"og:site_name\" content=\"Actualidad CEU\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UCHCEU\" \/>\n<meta property=\"article:published_time\" content=\"2014-01-28T09:59:41+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-02T11:47:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/medios.uchceu.es\/actualidad-ceu\/wp-content\/uploads\/sites\/2\/2014\/01\/Rosa-Lopez-Pedrajas_Medicina-CEU-UCH-Castello\u0081n.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1756\" \/>\n\t<meta property=\"og:image:height\" content=\"1217\" \/>\n\t<meta property=\"og:image:type\" 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Soriano","author_link":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/author\/tsoriano\/"},"uagb_comment_info":0,"uagb_excerpt":"The topiramate is able to prevent from the neural alterations observed in rats\u2019 brain after 20 days of cocaine administration. The topiramate is an antiepileptic drug which has the opposite effects of cocaine on the nervous system. A study realized by the professor of Medicine of the CEU Cardenal Herrera University in Castell\u00f3n, Rosa L\u00f3pez&hellip;","_links":{"self":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts\/110422","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/comments?post=110422"}],"version-history":[{"count":2,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts\/110422\/revisions"}],"predecessor-version":[{"id":160198,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/posts\/110422\/revisions\/160198"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/media\/98838"}],"wp:attachment":[{"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/media?parent=110422"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/categories?post=110422"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medios.uchceu.es\/actualidad-ceu\/en\/wp-json\/wp\/v2\/tags?post=110422"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}